小分子非编码RNAs在乳腺肿瘤中的作用机制
魏炎;楚慧丽;关雅萍;王俊;毕经旺;
摘要(Abstract):
小分子非编码RNAs由siRNA,miRNA,piRNA和snoRNA组成。研究证实miRNAs在乳腺肿瘤的发生过程中具有重要调控作用,其它三种非编码RNAs的功能尚未研究清楚。本文旨在探讨miRNA通过调节细胞生长周期的方式参与乳腺癌的发生发展过程及其对乳腺癌干细胞的调控功能,并对乳腺肿瘤中有关piRNA和snoRNA的实验证据进行了总结。
关键词(KeyWords): miRNA;非编码RNA;乳腺癌;致癌基因
基金项目(Foundation):
作者(Author): 魏炎;楚慧丽;关雅萍;王俊;毕经旺;
Email:
DOI:
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